Yeast Sporulation Case Study To examine the correlation between gene expression profiles and cell cycle stages

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Supervised Kmean analysis cluster up-regulated genes into seven temporal groups
In addition to the Gene Ontology Annotation Tool, the Yeast Function Catalog Annotation Tool also lets you examine the functions of your favorite gene list. Here shows the annotation of the 53 genes in the "metabolic" group
Comparing gene functions of the six temporal groups indicates good correlation between functions and cell cycle
Analyze the upstream sequences of genes in the ""metabolic" group reveals the URS1 motif, which implies the common transcriptional events for this group of genes